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Difference in gene switching discovered in different parts of brain - VT News

Sai Ma (left), a biomedical engineering and mechanics graduate student and first author of the paper, and Chang Lu, the Fred W. Bull Professor of Chemical Engineering, in their Goodwin Hall lab on Virginia Tech's Blacksburg campus. (right) 2018

Lu-Ma

Sai Ma (left), first author of the paper and a former biomedical engineering doctoral student, and Chang Lu, the Fred W. Bull Professor of Chemical Engineering at Virginia Tech.

April 26, 2018    

It is well-known that different parts of brain have drastically different functions. However, understanding how these different functions are sustained and regulated at the molecular level has been elusive.

In a study published in Science Advances, Chang Lu and his team found significant difference in the molecular machinery that turns on and off gene expression between the cerebellum and prefrontal cortex of a mouse brain. Their results provide clues to the molecular apparatus that is involved in conscious thinking in brains.

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